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Melatonin shows potential to slow tumor growth in certain breast cancers Date: January 28, 2014 Source: Henry Ford Health System Summary: An early stage study shows melatonin -- a hormone that regulates the body's sleep and awake cycles -- may have the potential to help slow the growth of certain breast cancer tumors, according to researchers.

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Overview of the regulatory environment, clinical patterns, and future directions in research with HDS; melatonin is not listed or discussed).

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Some, but not all, totally blind people whose retinae are intact, may benefit from light therapy.

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Strauss said. We have conventional treatments that are proven to be safe and effective and people are making individual decisions to neglect those therapies at some point.

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At night or in the dark, the pineal gland releases melatonin to regulate the sleep cycle.

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Altering the amount of one hormone in the body often alters the body's own production of other hormones.

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In their conclusion, the authors cautioned that chronic exposure to natural or artificial light and simultaneous intake of melatonin may potentially contribute to a significant loss of photoreceptor cells in the aging retina.

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Melatonin also alleviates some side effects of antipsychotics, such as weight gain and increased blood pressure.

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Reasonable increases in the dose of most opioids in response to poorly controlled pain do not tend to lead to an increased risk of adverse effects if a patient is tolerating the drug.

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In the study, the subjects, who did not know which treatment they were receiving, took melatonin an hour before bedtime for a period of weeks, then were switched to a dummy pill, or vice versa.

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There was a lack of good evidence, but guidance was offered nevertheless. Would we have been better off without any advice from the AAP.

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The problem is that the damage is harder to quantify and rarely reported. Who will measure the effects of bad information on health.

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People who have a history of depression, in particular, should discuss the use of melatonin with their doctors before taking it.

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The pairing of a lack of melatonin secretion and synthesis with weight gain suggests that melatonin may either be anti-obesogenic (reducing fat gain) or may induce fat loss.

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Pablo C. Okhuysen, profesor asociado de medicina de la divisin de enfermedades infecciosas de la facultad de medicina de la Universidad de Texas en Houston.

Melatonin has been proposed as therapy of sleep disturbances including insomnia and jet lag, but it has not been approved for this indication in the United States.

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In those species there are indications that melatonin stimulates the release of gonadotropin-inhibitory hormone, in turn leading to the suppression of (hormones that act on the ovaries or testes), which may explain the disruptive effects on reproduction.

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If the microbes are absent because, for example, they were eradicated through vaccination, the tumor will be encapsulated in scar tissue and stays in place with no further cell augmentation.

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Melatonin is produced by the pineal gland at night to regulate our circadian rhythm (sometimes called the sleep wake cycle).

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